ivive.app

Connect it to your AI

Claude Code

claude mcp add --transport http ivive https://api.ivive.app/mcp/

Claude, ChatGPT, Cursor and other apps

Add it as a custom connector with this URL (Streamable HTTP):

https://api.ivive.app/mcp/

Cursor, VS Code and other apps (mcp.json)

{
  "mcpServers": {
    "ivive": {
      "url": "https://api.ivive.app/mcp/"
    }
  }
}

Tools it offers

6 tools, as the server itself reported during our check on Oct 31, 2026.

• predict_inputsPredict fu,p and fu,inc from a SMILES, with structure-only human CL and Vss as second opinions. Predictions, not measurements; check the applicability verdict.
• calc_clhepHepatic and plasma clearance from in-vitro CLint, fu,mic and fu,p (IVIVE), with the observed-CL band and applicability warnings. If fu,p or fu,mic came from predict_inputs, tell the user the result rests on predicted inp
• target_clintThe in-vitro CLint an assay must read for a compound to reach a target plasma clearance (mL/min/kg): calc_clhep run backwards, e.g. to set a CLint cut-off for a screening cascade. Needs fu,mic and fu,p; refuses a target
• input_sensitivityHow far plasma CL moves as each input is varied over a range, e.g. a predicted fu,p over its 50% range.
• similar_drugsNearest reference drugs to a SMILES (Tanimoto, Morgan radius 2), each with measured human plasma CL and the CL IVIVE predicted from its measured inputs. Use it to judge how far to trust calc_clhep for this chemotype: if
• scale_to_humanPredict human plasma CL from observed animal in-vivo CL (rat, dog, monkey), every applicable method with its measured error. Observed animal CL only, never predicted.

Questions